Function of DNA polymerase - 500 Words

Function: of DNA polymerase DNA polymerase is a very important enzyme when it comes to DNA replication. DNA polymerase, more specifically, is involved in the process of reading and adding nucleotides to the DNA strand so a complimentary stand can be made. During the DNA replication process DNA polymerase puts new nucleotides on the 3’ end of the DNA Strand. Not only does DNA polymerase add nucleotides to a DNA strand it can also act somewhat as a â€Å"proof reader†. It can pause the replication process to fix mistakes that can occur during DNA replication. Once the sequencing mistake is identified DNA polymerase can get rid of the nucleotides and continue on with the replication process. DNA polymerase functions in many different processes†¦show more content†¦They found that the type of DNA polymerase in E.coli, DNA Polymerase III, has different characteristics in the nucleus that makes its catalyzing action nonexistent. In the experiment they tried to reintr oduce the nuclease from other bacteria into the E.coli. The results show that E.coli has evolved differently than other bacteria and may use a different process to proof reading DNA, but the PHP does play a role in the structure and activity of DNA polymerase III (Barros, Guenther, Kelch, Anaya, Prabhakar, ODonnell Lamers, 2013). A structural role for the PHP domain in E. coli DNA polymerase III. BMC Structural Biology, 13(1), 1-12. doi:10.1186/1472-6807-13-8. DNA polymerase can have a particular function when it comes do different diseases or conditions. DNA polymerase has a specific function in the treatment of hepatitis B. The hepatitis B virus depends on a type of DNA polymerase called reverse transcriptase. When patients that are given a class of medication called analogue nucleosides. This medication specifically targets the DNA polymerase in the Hepatitis B Virus. In some Hepatitis B cases the DNA polymerase mutates in the presence of the treatment casing a resistance (Ngu yen, Garcia, Trinh, Nguyen, Nguyen, Nguyen, Levitt, 2009). It also can be seen in research to try to stop cancerous growth. DNAShow MoreRelatedExploring Protein Structure With The Molecular Visualization Firstglance1041 Words   |  5 Pagesusing the FirstGlance in Jmol molecular visualization to examine key structural features of proteins. This work is important because protein structure can be related to function, multiple-sequence alignments and evolutionary preservation, and designing drug. FirstGlance in Jmol makes it fairly easy to perceive structure-function relationships in the protein you chose. Using FirstGlance, it is easy to visualize and distinguish chains, and disulfide bonds are obvious. Alpha helices and beta strandsRead MoreDna Protein Protein Structure1707 Words   |  7 PagesDNA Polymerase Proteins are arguably the most structurally and functionally complex structures known to man. Through evolution spanning billions of years, these macromolecules have been perfected to perform many functions necessary for life. Proteins contain four distinct levels of structure and are composed of simple organic compounds known as amino acids. (Alberts, Bruce et al 2000) Amino acids are joined together by peptide bonds made during protein biosynthesis, and the linked amino acid chainRead MoreWhat Does It Mean For Dna Replication?991 Words   |  4 Pagesdoes it mean for DNA replication to be semi- conservative? Semiconservative replication means during DNA replication each DNA strand is used to make new template of DNA from the 2 parental strands of DNA (Thompson, Part 1: DNA Replication, 2014). During this replication is to ensure that the newly replicated cells have the same full set of DNA as the parent cells so the sequence will continue to work properly (Thompson, Part 1: DNA Replication, 2014). During the process of DNA replication, the strandsRead MoreGene expression is the process of protein formation. Proteins are the molecules that are900 Words   |  4 Pagesalso known as DNA in humans. DNA is a double stranded molecule comprising of a sugar-phosphate backbone and nitrogenous bases. On a smaller scale, DNA is made up of complementary nucleotide sequences. There are four different nucleotides: adenine (A), cytosine (C), guanine (G) and thymine (T). Humans have approximately 3 billion of these base pairs. However, not all of them are coding sequences. Approximately 1.3% of the DN A codes for proteins, the rest, have many varied functions that are stillRead MoreAbstract. Taq Polymerase Is Essential In Polymerase Chain1446 Words   |  6 Pages ABSTRACT Taq Polymerase is essential in Polymerase Chain Reaction(PCR) experiments to obtain a PCR amplification of an unknown gene. The unknown gene is then ligated into a vector plasmid, which is placed in a bacterium Escherichia Coli to transform and multiply. Ultimately, identification and characterization of the unknown gene is done using electrophoreses and gel imaging. Cloning techniques such as the one performed have been used for many years to isolate genes from a variety of species.Read MoreDescription And Function Of Mutagenesis1345 Words   |  6 PagesSite-directed mutagenesis is a method used to construct amino acid changes in a protein in order to test the function of a specific amino acid. It is the way to study protein structure and function change the amino acid sequence of a protein by altering the DNA sequence of cloned gene4. A particular amino acid is very important in catalytic activity, ligand binding, protein folding or other function. Amino acid residue significanc e is tested by making conservative substitutions or by changing the aminoRead MoreTask1 Essay783 Words   |  4 Pagesï » ¿Biochemistry Competence 208.5.1: DNA,RNA Nicole Seegmiller-Mott Western Governors University Abstract This a brief written report on the role of DNA, RNA and transmission on information within a cell to create amino acids. Biochemistry Competence 208.5.1: DNA,RNA DNA replication is an intricate process that requires many different proteins. Each protein preforms a very specific function in the creation of a new DNA strand. First helicase works by unwinding or dividing the original double helixRead MoreEssay about The Question of Biology is Why?1518 Words   |  7 Pageswill be analyzing two very different processes: DNA Replication and the Polymerase Chain Reaction (PCR). It is that each of these individual processes carries much importance. DNA replication is important in the life of a cell, more so the division, because when a cell divides both of the daughter cells need identical DNA to function properly. PCR is important in that it allows amplification of DNA and isolation of DNA. PCR is also used to analyze DNA samples (used widely in crime scene investigationRead MoreStructure and Function of Nucleolus883 Words   |  4 Pagesribosomes. However, it has been proposed that this particular organization is only observed in higher eukary otes and that it evolved from a bipartite organization with the transition from anamniotes to amniotes. Reflecting the substantial increase in the DNA intergenic region, an original fibrillar component would have separated into the FC and the DFC. Another structure identified within many nucleoli (particularly in plants) is a clear area in the center of the structure referred to as a nucleolar vacuoleRead MoreDna Is A Polymer Of Nucleotides1181 Words   |  5 PagesDNA is a polymer of nucleotides, each consisting of three components. These components include a nitrogenous base, a deoxyribose sugar and a phosphate group. The hydrophobic nitrogenous bases are in the DNA molecules interior with the negatively charged phosphate groups on the outside. Strong covalent bonds link each unit of the nucleotide together. Between the stacked pairs Van der Waals interactions play an important role in holding the molecule together. There are four different bases called adenine

Maria Montessori From Marginal to Mainstream Essay

Maria Montessori: From Marginal to Mainstream Biographical Background When I was at school we had a teacher whose fixed idea was to make us learn the lives of famous women, in order to incite us to imitate them. The exhortation which accompanied the narration was always the same: You too should try to become famous. Would you not like to become famous? Oh no, I replied drily one day, I shall never be that. I care to much for the children of the future to add yet another biography to the list. --Maria Montessori Maria Montessori was born in the town of Chiravalle in the province of Ancona August 31, 1870, the same year Italy became a unified Nation. Her parent were Alessandro Montessori and Renilde Stopanni, niece of the†¦show more content†¦One room, she told the other girl, seemed just as good to her as another. Yet, upon discovering that she learned easily and did well on her exams, Maria concluded it would be nonsense not to do so. From that time on, Maria became and avid scholar. At the age of twelve, Maria decided she wanted to continue her education. It was unusual for girls in Italy at this time to go beyond and elementary education and those who did usually pursued classical studies. Maria, however, decided she wanted to go to a technical school. In the fall of 1883, shortly after her thirteenth birthday, Maria entered the Regia Scuola Tecnica Michelangelo Buonarroti.Maria graduated from the technical school in 1886 with high marks in all subjects. From 1886 to 1889 she attended the technical institute, the Regia Instituto Tecnica Leonardo da Vinci, and continued to do well. She excelled in her favorite subject, mathematics, and had plans of becoming an engineer. Ironically, she refused to even consider teaching, thought to be one of the only lady-like professions available, as a future career. As her graduation from the technical school drew close, Maria changed her mind about becoming an engineer. Following hr increasing interest in biological sciences, she decided to go on to the University to study medicine, something no woman in Italy had ever done before. In 1890, despite the disapproval of her relatives, her father in particular, and that of Guido Baccelli, the

Radiology Tech free essay sample

For many years I was influenced by the work of some young ambitious doctors, and I truly admired their courage, determination and dedication to their noble profession. Now, I am particularly interested in radiologic technology, because nowadays it is having wide application and enjoying good demand in medical circles, in particular, sonography, MR tomography or other diagnostic imaging techniques. The role of radiologic technologists in diagnosing various diseases is significant, because within the last decades, modern radiologic technology has been significantly developing. Now it allows detecting and monitoring a huge variety of injuries or malfunctions of the organs of human organism, starting from bone fractures and ending with different forms of cancer. I am particularly attracted by this occupation due to its dynamism, flexibility and opportunity to deal with the patients, who have different types of health problems. I think that I have good social skills and personal qualities for doing this job well, because I always like working and communicating with people, supporting them, looking for ways to give them positive emotions and stimulate their will for recovery. We will write a custom essay sample on Radiology Tech or any similar topic specifically for you Do Not WasteYour Time HIRE WRITER Only 13.90 / page It is also important that becoming a radiologic technologist will allow me to specialize at a number of prospective clinical areas. In particular, it is possible to specialize on MR imaging, which is highly applied in detecting pathologic tissues in human brains, etc. Modern sonography has also very wide diagnostic application, starting form obstetrics and ending with vascular medicine. The other opportunities include cardiovascular-interventional radiography, computed tomography, mammography, nuclear medicine, and others. In addition to everything above, I am considering becoming a member of the team which works on detecting and treating different types of cancer. I understand that patients with cancer are in need of special care. Moreover, frequently they need some physical help or psychological support and attention, and I believe that I have all necessary resources to provide them with this. Besides, I am a good and responsible team member. I always enjoy any form of collaboration with other people on solving one or another problem, because it brings me more opportunities to socialize and to learn new things. I suppose that, generally, my professional responsibilities as a radiologic technologist will include interviewing people and obtaining accurate information about their health condition; performing all required technical diagnostic procedures (like electrocardiograms, basic X-rays, MR or other imaging, etc. ); analyzing the information received in order to facilitate the process of making correct diagnosis; assisting physicians and other specialists in providing patients with quality medical care, etc. I know that nowadays, radiologic technologists are in very good demand and it is not a problem for these specialists to find a job in a hospital or a clinic. Probably, after receiving the certificate, I will choose to be back to my hometown and look for the opportunities to start my professional career in a public hospital, diagnostic center or medical laboratory. I suppose, I’ll find there perfect environment for gaining proper professional experience and obtaining all necessary qualities to advance as a sufficient medical specialist. I think that I am highly motivated and challenged to succeed in my chosen future occupation: medicine. It is the greatest ambition of my life to find myself in this most humanistic and respectable professions on earth, which is my true honorable calling. I believe that this job will bring me good reward and a lot of satisfaction, as well as numerous opportunities for personal development and growth. Bibliography: †¢ Radiologic Technologists and Technicians. (2006, August 4). Occupational Outlook Handbook by Bureau of Labor Statistics, the U. S. Department of Labor. Retrieved February 27, 2007, from the World Wide Web: .

Was The Man We Know As Shakespeare Really The Author Of Essays

Was the man we know as Shakespeare really the author of the "Shakespearean Works"? We know little about the man called Shakespeare, Did he really write the plays, or is he just a man that got confused within history? (Sobran 44) There is not even a correct spelling of this mans name, Some of the spellings include Shakspere, Shakespeare, And Shaxpere. Shakespeare, Is it the man, Or is it another? (Hayes 1D) Shakespeare is both fact and fiction, he was no concern until nearly two hundred years after he perished, and there is still no definite or probably will there ever be a conclusion to this mystery. (Sobran 44) There is another man that can be attributed with the works of "Shakespeare", His name is Edward DeVere, the 17th Earl of Oxford. (Bethell 47) The man known as Shakespeare does not fit perfectly into the necessary criteria to determine the author of these works. Thomas Looney invented a series of criteria that had to be filled, in order to be a possible candidate for the authorship of the Shakespearean works. To have all the knowledge that is portrayed in the works, the author must have accomplished many things. These including a superior education, from what we know of "Shakespeare", this was not a possibility.(Bethell 46) We do not even know if Shakespeare has ever written anything in his life, Nor do we know that he was paid for writing these works. The man Shakespeare does not even make a claim that he is the author.(Bethell 50) He may not have been able to write the simplest thing of all, His own name.(Hayes 1D) Its not how little we know about Shakespeare that causes confusion and difficulty, Its the things that we do know about this man that cause the confusion and difficulty. We know Shakespears father, a glover, could not write. When he signed documents, he simply made an "X", This is why it is beleived that Shakespeare could not write also, Because he probably did not attend school therefore his education was passed down from his father. (Bethell 48) We do know much more about the man Edward DeVere. We know that because deVere was a nobleman, he could not have his name written upon his writings because he would be considered of a lower class. The plays contain a sense of hate towards some of the noblemen of that time period, which also point the authorship towards DeVere. (Hayes 1D) When DeVere was a young man, he spent a lot of time in Italy and Europe, This could explain the great detail used in the Shakespearean plays of Venice, and other European locations.(Sobran 45) The sonnets have never been able to fit into Shakespears life, On the other hand they fit into DeVere's life well. (Sobran 45) There are facts that lean both ways in this age old mystery of authorship, Though the Strafordian man does not fit into the story very well, He may have some advantages that the Oxfordian man may not. DeVere on the other hand, has mostly every fact pointing towards him as the valid author for the "Shakespearean" works, From his education, to his experiences, to his travel. The Oxfordian seems to come out on top. Shakespeare: Stratforidan, or DeVere?